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Shirin Bruderer Selected Research

macitentan

12/2019Effect of Macitentan on the Pharmacokinetics of the Breast Cancer Resistance Protein Substrates, Rosuvastatin and Riociguat, in Healthy Male Subjects.
1/2013Pharmacokinetics of macitentan in caucasian and Japanese subjects: the influence of ethnicity and sex.
9/2012Absorption, distribution, metabolism, and excretion of macitentan, a dual endothelin receptor antagonist, in humans.
3/2012Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist.

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Shirin Bruderer Research Topics

Disease

11Pulmonary Arterial Hypertension
01/2021 - 03/2012
2Nausea
12/2017 - 06/2017
2Headache (Headaches)
12/2017 - 06/2017
1Breast Neoplasms (Breast Cancer)
12/2019
1Vomiting
12/2017
1Pain (Aches)
06/2017
1Diarrhea
06/2017

Drug/Important Bio-Agent (IBA)

7selexipagIBA
01/2021 - 01/2014
6Epoprostenol ReceptorsIBA
01/2021 - 01/2014
4Endothelin Receptor AntagonistsIBA
12/2019 - 03/2012
4macitentanIBA
12/2019 - 03/2012
3Epoprostenol (Prostacyclin)FDA LinkGeneric
06/2017 - 06/2015
2ProstaglandinsIBA
02/2018 - 06/2017
1Rosuvastatin Calcium (Crestor)FDA Link
12/2019
1Proteins (Proteins, Gene)FDA Link
12/2019
1riociguatIBA
12/2019
1(4- ((5,6- diphenylpyrazin- 2- yl)(isopropyl)amino)butoxy)acetic acidIBA
12/2017
1Warfarin (Coumadin)FDA LinkGeneric
05/2016